Biology Seminar: Ian Jan
Human 2D gastruloids model the spatial patterning that occurs during gastrulation, which is otherwise inaccessible because of ethical and technical limitations. Specifically, this highly reproducible system enables quantitative analysis of cell signaling and fate decisions during embryogenesis. Although gastruloids can provide insights into the molecular mechanisms underlying early embryonic development, their potential for large-scale screens is limited by low-throughput analytical approaches.